Ontology highlight
ABSTRACT:
SUBMITTER: Sayols-Baixeras S
PROVIDER: S-EPMC4844221 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Sayols-Baixeras Sergi S Lluís-Ganella Carla C Subirana Isaac I Salas Lucas A LA Vilahur Nadia N Corella Dolores D Muñoz Dani D Segura Antonio A Jimenez-Conde Jordi J Moran Sebastián S Soriano-Tárraga Carolina C Roquer Jaume J Lopez-Farré Antonio A Marrugat Jaume J Fitó Montse M Elosua Roberto R
Epigenetics 20150101 12
Smoking increases the risk of many diseases and could act through changes in DNA methylation patterns. The aims of this study were to determine the association between smoking and DNA methylation throughout the genome at cytosine-phosphate-guanine (CpG) site level and genomic regions. A discovery cross-sectional epigenome-wide association study nested in the follow-up of the REGICOR cohort was designed and included 645 individuals. Blood DNA methylation was assessed using the Illumina HumanMethy ...[more]