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Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders.


ABSTRACT: Biohybrid microcylinders are fabricated using electrohydrodynamic cojetting followed by a surface chemistry approach to maximize cell-adhesive characteristics. As proper cell alignment and mechanical stiffness are important components of bioactuator design, spatial cell selectivity and stress/strain properties of microcylinders are characterized to demonstrate their capability of response to rat cardio-myocyte contraction. These microcylinders can find applications in a host of micromechanical systems.

SUBMITTER: Yoon J 

PROVIDER: S-EPMC4844906 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature

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Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders.

Yoon Jaewon J   Eyster Tom W TW   Misra Asish C AC   Lahann Joerg J  

Advanced materials (Deerfield Beach, Fla.) 20150624 30


Biohybrid microcylinders are fabricated using electrohydrodynamic cojetting followed by a surface chemistry approach to maximize cell-adhesive characteristics. As proper cell alignment and mechanical stiffness are important components of bioactuator design, spatial cell selectivity and stress/strain properties of microcylinders are characterized to demonstrate their capability of response to rat cardio-myocyte contraction. These microcylinders can find applications in a host of micromechanical s  ...[more]

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