Multivariate meta-analysis using individual participant data.
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ABSTRACT:
SUBMITTER: Riley RD
PROVIDER: S-EPMC4847645 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Publications
Multivariate meta-analysis using individual participant data.
Riley R D RD Price M J MJ Jackson D D Wardle M M Gueyffier F F Wang J J Staessen J A JA White I R IR
Research synthesis methods 20141121 2
When combining results across related studies, a multivariate meta-analysis allows the joint synthesis of correlated effect estimates from multiple outcomes. Joint synthesis can improve efficiency over separate univariate syntheses, may reduce selective outcome reporting biases, and enables joint inferences across the outcomes. A common issue is that within-study correlations needed to fit the multivariate model are unknown from published reports. However, provision of individual participant dat ...[more]
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