Translational Control during Calicivirus Infection.
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ABSTRACT:
SUBMITTER: Royall E
PROVIDER: S-EPMC4848598 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Publications
Translational Control during Calicivirus Infection.
Royall Elizabeth E Locker Nicolas N
Viruses 20160420 4
In this review, we provide an overview of the strategies developed by caliciviruses to subvert or regulate the host protein synthesis machinery to their advantage. As intracellular obligate parasites, viruses strictly depend on the host cell resources to produce viral proteins. Thus, many viruses have developed strategies that regulate the function of the host protein synthesis machinery, often leading to preferential translation of viral mRNAs. Caliciviruses lack a 5' cap structure but instead ...[more]
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