MicroRNAs in Hyperglycemia Induced Endothelial Cell Dysfunction.
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ABSTRACT:
SUBMITTER: Silambarasan M
PROVIDER: S-EPMC4848974 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
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MicroRNAs in Hyperglycemia Induced Endothelial Cell Dysfunction.
Silambarasan Maskomani M Tan Jun Rong JR Karolina Dwi Setyowati DS Armugam Arunmozhiarasi A Kaur Charanjit C Jeyaseelan Kandiah K
International journal of molecular sciences 20160407 4
Hyperglycemia is closely associated with prediabetes and Type 2 Diabetes Mellitus. Hyperglycemia increases the risk of vascular complications such as diabetic retinopathy, diabetic nephropathy, peripheral vascular disease and cerebro/cardiovascular diseases. Under hyperglycemic conditions, the endothelial cells become dysfunctional. In this study, we investigated the miRNA expression changes in human umbilical vein endothelial cells exposed to different glucose concentrations (5, 10, 25 and 40 m ...[more]
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