Fatigue and Comorbidities in Multiple Sclerosis.

ABSTRACT:

Background

Fatigue is commonly reported by people with multiple sclerosis (MS). Comorbidity is also common in MS, but its association with the presence of fatigue or fatigue changes over time is poorly understood.

Methods

Nine hundred forty-nine people with definite MS were recruited from four Canadian centers. The Fatigue Impact Scale for Daily Use and a validated comorbidity questionnaire were completed at three visits over 2 years. Participants were classified into groups with no fatigue versus any fatigue. Logistic regression was used to determine the relationship between fatigue and each comorbidity at baseline, year 1, year 2, and overall.

Results

The incidence of fatigue during the study was 38.8%. The prevalence of fatigue was greater in those who were older (

SUBMITTER: Fiest KM 

PROVIDER: S-EPMC4849402 | biostudies-literature | 2016 Mar-Apr

REPOSITORIES: biostudies-literature