Ontology highlight
ABSTRACT:
SUBMITTER: Luo Y
PROVIDER: S-EPMC4851109 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Luo Yuping Y Coskun Volkan V Liang Aibing A Yu Juehua J Cheng Liming L Ge Weihong W Shi Zhanping Z Zhang Kunshan K Li Chun C Cui Yaru Y Lin Haijun H Luo Dandan D Wang Junbang J Lin Connie C Dai Zachary Z Zhu Hongwen H Zhang Jun J Liu Jie J Liu Hailiang H deVellis Jean J Horvath Steve S Sun Yi Eve YE Li Siguang S
Cell 20150501 5
The scarcity of tissue-specific stem cells and the complexity of their surrounding environment have made molecular characterization of these cells particularly challenging. Through single-cell transcriptome and weighted gene co-expression network analysis (WGCNA), we uncovered molecular properties of CD133(+)/GFAP(-) ependymal (E) cells in the adult mouse forebrain neurogenic zone. Surprisingly, prominent hub genes of the gene network unique to ependymal CD133(+)/GFAP(-) quiescent cells were enr ...[more]