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Immunotherapy for non-small cell lung cancer: current concepts and clinical trials.


ABSTRACT: Recent successes in immunotherapeutic strategies are being investigated to combat cancers that have less than ideal responses to standard of care treatment, such as non-small-cell lung cancer. In this paper, we summarize concepts and the current status of immunotherapy for non-small cell lung cancer, including salient features of the major categories of immunotherapy-monoclonal antibody therapy, immune checkpoint blockade, immunotoxins, anticancer vaccines, and adoptive cell therapy.

SUBMITTER: Mayor M 

PROVIDER: S-EPMC4851162 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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Immunotherapy for non-small cell lung cancer: current concepts and clinical trials.

Mayor Marissa M   Yang Neng N   Sterman Daniel D   Sterman Daniel D   Jones David R DR   Adusumilli Prasad S PS  

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20151029 5


Recent successes in immunotherapeutic strategies are being investigated to combat cancers that have less than ideal responses to standard of care treatment, such as non-small-cell lung cancer. In this paper, we summarize concepts and the current status of immunotherapy for non-small cell lung cancer, including salient features of the major categories of immunotherapy-monoclonal antibody therapy, immune checkpoint blockade, immunotoxins, anticancer vaccines, and adoptive cell therapy. ...[more]

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