Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC4852925 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Zhang Long L Lu Lu L Li Siming S Zhang Guolong G Ouyang Linghua L Robinson Kelsy K Tang Yanqiang Y Zhu Qing Q Li Diyan D Hu Yaodong Y Liu Yiping Y
PloS one 20160502 5
Host defense peptides (HDPs) play a critical role in innate immunity. Specific modulation of endogenous HDP synthesis by dietary compounds has been regarded as a novel approach to boost immunity and disease resistance in animal production. 1,25-dihydroxy vitamin D3 (1,25D3) is well known as a powerful HDP inducer in humans, but limited information about the effect of 1,25D3 on HDPs in poultry is available. Here, we sought to examine whether 1,25D3 could stimulate avian β-defensin (AvBD) expressi ...[more]