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ABSTRACT: Background
Persistent severe left ventricular (LV) systolic dysfunction after myocardial infarction (MI) is associated with increased mortality and is a class I indication for implantation of a cardioverter-defibrillator.Objectives
This study developed models and assessed independent predictors of LV recovery to >35% and ≥50% after 90-day follow-up in patients presenting with acute MI and severe LV dysfunction.Methods
Our multicenter prospective observational study enrolled participants with ejection fraction (EF) of ≤35% at the time of MI (n = 231). Predictors for EF recovery to >35% and ≥50% were identified after multivariate modeling and validated in a separate cohort (n = 236).Results
In the PREDICTS (PREDiction of ICd Treatment Study) study, 43% of pati
SUBMITTER: Brooks GC
PROVIDER: S-EPMC4854198 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature