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Coordination of gene expression between organellar and nuclear genomes.

ABSTRACT: Following the acquisition of chloroplasts and mitochondria by eukaryotic cells during endosymbiotic evolution, most of the genes in these organelles were either lost or transferred to the nucleus. Encoding organelle-destined proteins in the nucleus allows for host control of the organelle. In return, organelles send signals to the nucleus to coordinate nuclear and organellar activities. In photosynthetic eukaryotes, additional interactions exist between mitochondria and chloroplasts. Here we review recent advances in elucidating the intracellular signalling pathways that coordinate gene expression between organelles and the nucleus, with a focus on photosynthetic plants.

SUBMITTER: Woodson JD

PROVIDER: S-EPMC4854206 | biostudies-literature | 2008 May

REPOSITORIES: biostudies-literature

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Coordination of gene expression between organellar and nuclear genomes.

Woodson Jesse D JD Chory Joanne J

Nature reviews. Genetics 20080501 5

Following the acquisition of chloroplasts and mitochondria by eukaryotic cells during endosymbiotic evolution, most of the genes in these organelles were either lost or transferred to the nucleus. Encoding organelle-destined proteins in the nucleus allows for host control of the organelle. In return, organelles send signals to the nucleus to coordinate nuclear and organellar activities. In photosynthetic eukaryotes, additional interactions exist between mitochondria and chloroplasts. Here we rev ...[more]

PMID: 18368053

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