Ontology highlight
ABSTRACT:
SUBMITTER: Lee HJ
PROVIDER: S-EPMC4854545 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Epigenetics 20160310 3
Spermatogonial stem cells (SSCs), which are unipotent stem cells in the testes that give rise to sperm, can be converted into germline-derived pluripotent stem (gPS) by self-induction. The androgenetic imprinting pattern of SSCs is maintained even after their reprogramming into gPS cells. In this study, we used an in vitro neural differentiation model to investigate whether the imprinting patterns are maintained or altered during differentiation. The androgenetic patterns of H19, Snrpn, and Mest ...[more]