Ontology highlight
ABSTRACT:
SUBMITTER: Daboussi L
PROVIDER: S-EPMC4855891 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Daboussi Lydia L Costaguta Giancarlo G Payne Gregory S GS
Nature cell biology 20120219 3
Clathrin-coated vesicles mediate endocytosis and transport between the trans-Golgi network (TGN) and endosomes in eukaryotic cells. Clathrin adaptors play central roles in coat assembly, interacting with clathrin, cargo and membranes. Two main types of clathrin adaptor act in TGN-endosome traffic: GGA proteins and the AP-1 complex. Here we characterize the relationship between GGA proteins, AP-1 and other TGN clathrin adaptors using live-cell and super-resolution microscopy in yeast. We present ...[more]