Ontology highlight
ABSTRACT:
SUBMITTER: Aschenbrenner J
PROVIDER: S-EPMC4856998 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Aschenbrenner Joos J Marx Andreas A
Nucleic acids research 20160325 8
Methylation of the 2'-hydroxyl-group of ribonucleotides is found in all major classes of RNA in eukaryotes and is one of the most abundant posttranscriptional modifications of stable RNAs. In spite of intense studies, the multiple functions of RNA 2'-O-methylation are still not understood. One major obstacle in the field are the technical demanding detection methods, which are typically laborious and do not always deliver unambiguous results. We present a thermostable KlenTaq DNA polymerase vari ...[more]