Ontology highlight
ABSTRACT:
SUBMITTER: Baati T
PROVIDER: S-EPMC4858730 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Baati Tarek T Al-Kattan Ahmed A Esteve Marie-Anne MA Njim Leila L Ryabchikov Yury Y Chaspoul Florence F Hammami Mohamed M Sentis Marc M Kabashin Andrei V AV Braguer Diane D
Scientific reports 20160506
Si/SiOx nanoparticles (NPs) produced by laser ablation in deionized water or aqueous biocompatible solutions present a novel extremely promising object for biomedical applications, but the interaction of these NPs with biological systems has not yet been systematically examined. Here, we present the first comprehensive study of biodistribution, biodegradability and toxicity of laser-synthesized Si-SiOx nanoparticles using a small animal model. Despite a relatively high dose of Si-NPs (20 mg/kg) ...[more]