Proteoglycan form and function: A comprehensive nomenclature of proteoglycans.
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ABSTRACT:
SUBMITTER: Iozzo RV
PROVIDER: S-EPMC4859157 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Publications
Proteoglycan form and function: A comprehensive nomenclature of proteoglycans.
Iozzo Renato V RV Schaefer Liliana L
Matrix biology : journal of the International Society for Matrix Biology 20150218
We provide a comprehensive classification of the proteoglycan gene families and respective protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular location, overall gene/protein homology, and the utilization of specific protein modules within their respective protein cores. These three signatures were utilized to design four major classes of proteoglycans with distinct forms and functions: the intracellular, cell-surface, pericellular and extracellular prote ...[more]
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