Ontology highlight
ABSTRACT:
SUBMITTER: Jiang SY
PROVIDER: S-EPMC4860697 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Jiang Shu-Ye SY Ramachandran Srinivasan S
Genome biology and evolution 20160425 4
DNA glycosylases catalyze the release of methylated bases. They play vital roles in the base excision repair pathway and might also function in DNA demethylation. At least three families of DNA glycosylases have been identified, which included 3'-methyladenine DNA glycosylase (MDG) I, MDG II, and HhH-GPD (Helix-hairpin-Helix and Glycine/Proline/aspartate (D)). However, little is known on their genome-wide identification, expansion, and evolutionary history as well as their expression profiling a ...[more]