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Integrative NMR for biomolecular research.

ABSTRACT: NMR spectroscopy is a powerful technique for determining structural and functional features of biomolecules in physiological solution as well as for observing their intermolecular interactions in real-time. However, complex steps associated with its practice have made the approach daunting for non-specialists. We introduce an NMR platform that makes biomolecular NMR spectroscopy much more accessible by integrating tools, databases, web services, and video tutorials that can be launched by simple installation of NMRFAM software packages or using a cross-platform virtual machine that can be run on any standard laptop or desktop computer. The software package can be downloaded freely from the NMRFAM software download page ( http://pine.nmrfam.wisc.edu/download_packages.html ), and detailed instructions are available from the Integrative NMR Video Tutorial page ( http://pine.nmrfam.wisc.edu/integrative.html ).

SUBMITTER: Lee W

PROVIDER: S-EPMC4861749 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature

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Integrative NMR for biomolecular research.

Lee Woonghee W Cornilescu Gabriel G Dashti Hesam H Eghbalnia Hamid R HR Tonelli Marco M Westler William M WM Butcher Samuel E SE Henzler-Wildman Katherine A KA Markley John L JL

Journal of biomolecular NMR 20160329 4

NMR spectroscopy is a powerful technique for determining structural and functional features of biomolecules in physiological solution as well as for observing their intermolecular interactions in real-time. However, complex steps associated with its practice have made the approach daunting for non-specialists. We introduce an NMR platform that makes biomolecular NMR spectroscopy much more accessible by integrating tools, databases, web services, and video tutorials that can be launched by simple ...[more]

PMID: 27023095

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