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Complete Nucleotide Sequence of pKOI-34, an IncL/M Plasmid Carrying blaIMP-34 in Klebsiella oxytoca Isolated in Japan.


ABSTRACT: We determined the complete nucleotide sequence of a self-transmissible IncL/M plasmid, pKOI-34, from a Klebsiella oxytoca isolate. pKOI-34 possessed the core structure of an IncL/M plasmid found in Erwinia amylovora, pEL60, with two mobile elements inserted, a transposon carrying the arsenic resistance operon and a Tn21-like core module (tnp and mer modules) piggybacking blaIMP-34 as a class 1 integron, In808, where blaIMP-34 confers a resistance to carbapenems in K. oxytoca and Klebsiella pneumoniae.

SUBMITTER: Shimada N 

PROVIDER: S-EPMC4862478 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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Complete Nucleotide Sequence of pKOI-34, an IncL/M Plasmid Carrying blaIMP-34 in Klebsiella oxytoca Isolated in Japan.

Shimada Norimitsu N   Kayama Shizuo S   Shigemoto Norifumi N   Hisatsune Junzo J   Kuwahara Ryuichi R   Nishio Hisaaki H   Yamasaki Katsutoshi K   Wada Yasunao Y   Sueda Taijiro T   Ohge Hiroki H   Sugai Motoyuki M  

Antimicrobial agents and chemotherapy 20160422 5


We determined the complete nucleotide sequence of a self-transmissible IncL/M plasmid, pKOI-34, from a Klebsiella oxytoca isolate. pKOI-34 possessed the core structure of an IncL/M plasmid found in Erwinia amylovora, pEL60, with two mobile elements inserted, a transposon carrying the arsenic resistance operon and a Tn21-like core module (tnp and mer modules) piggybacking blaIMP-34 as a class 1 integron, In808, where blaIMP-34 confers a resistance to carbapenems in K. oxytoca and Klebsiella pneum  ...[more]

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