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Fecal Microbiota Transplantation Inhibits Multidrug-Resistant Gut Pathogens: Preliminary Report Performed in an Immunocompromised Host.


ABSTRACT: Colonization of the gastrointestinal tract with multidrug-resistant (MDR) bacteria is a consequence of gut dysbiosis. We describe the successful utilization of fecal microbiota transplantation to inhibit Klebsiella pneumoniae MBL(+) and Escherichia coli ESBL(+) gut colonization in the immunocompromised host as a novel tool in the battle against MDR microorganisms. ClinicalTrials.gov identifier NCT02461199.

SUBMITTER: Bilinski J 

PROVIDER: S-EPMC4863031 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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Fecal Microbiota Transplantation Inhibits Multidrug-Resistant Gut Pathogens: Preliminary Report Performed in an Immunocompromised Host.

Biliński Jarosław J   Grzesiowski Paweł P   Muszyński Jacek J   Wróblewska Marta M   Mądry Krzysztof K   Robak Katarzyna K   Dzieciątkowski Tomasz T   Wiktor-Jedrzejczak Wiesław W   Basak Grzegorz W GW  

Archivum immunologiae et therapiae experimentalis 20160309 3


Colonization of the gastrointestinal tract with multidrug-resistant (MDR) bacteria is a consequence of gut dysbiosis. We describe the successful utilization of fecal microbiota transplantation to inhibit Klebsiella pneumoniae MBL(+) and Escherichia coli ESBL(+) gut colonization in the immunocompromised host as a novel tool in the battle against MDR microorganisms. ClinicalTrials.gov identifier NCT02461199. ...[more]

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