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Stem cell secretome-rich nanoclay hydrogel: a dual action therapy for cardiovascular regeneration.

ABSTRACT: A nanocomposite hydrogel with photocrosslinkable micro-porous networks and a nanoclay component was successfully prepared to control the release of growth factor-rich stem cell secretome. The proven pro-angiogenic and cardioprotective potential of this new bioactive system provides a valuable therapeutic platform for cardiac tissue repair and regeneration.

SUBMITTER: Waters R 

PROVIDER: S-EPMC4863075 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature

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Stem cell secretome-rich nanoclay hydrogel: a dual action therapy for cardiovascular regeneration.

Waters Renae R   Pacelli Settimio S   Maloney Ryan R   Medhi Indrani I   Ahmed Rafeeq P H RP   Paul Arghya A  

Nanoscale 20160401 14

A nanocomposite hydrogel with photocrosslinkable micro-porous networks and a nanoclay component was successfully prepared to control the release of growth factor-rich stem cell secretome. The proven pro-angiogenic and cardioprotective potential of this new bioactive system provides a valuable therapeutic platform for cardiac tissue repair and regeneration. ...[more]

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