Ontology highlight
ABSTRACT:
SUBMITTER: Halvorsen AR
PROVIDER: S-EPMC4863128 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Halvorsen Ann R AR Silwal-Pandit Laxmi L Meza-Zepeda Leonardo A LA Vodak Daniel D Vu Phuong P Sagerup Camilla C Hovig Eivind E Myklebost Ola O Børresen-Dale Anne-Lise AL Brustugun Odd T OT Helland Åslaug Å
Frontiers in genetics 20160511
<h4>Background</h4>TP53 mutations are among the most common mutations found in lung cancers, identified as an independent prognostic factor in many types of cancers. The purpose of this study was to investigate the frequency and prognostic impact of TP53 mutations in never-smokers and in different histological subtypes of lung cancer.<h4>Methods</h4>We analyzed tumor tissue from 394 non-small cell carcinomas including adenocarcinomas (n = 229), squamous cell carcinomas (n = 112), large cell carc ...[more]