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Highly Elastic and Conductive Human-Based Protein Hybrid Hydrogels.

ABSTRACT: A highly elastic hybrid hydrogel of methacryloyl-substituted recombinant human tropoelastin (MeTro) and graphene oxide (GO) nanoparticles are developed. The synergistic effect of these two materials significantly enhances both ultimate strain (250%), reversible rotation (9700°), and the fracture energy (38.8 ± 0.8 J m(-2) ) in the hybrid network. Furthermore, improved electrical signal propagation and subsequent contraction of the muscles connected by hybrid hydrogels are observed in ex vivo tests.

SUBMITTER: Annabi N

PROVIDER: S-EPMC4863466 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature

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Highly Elastic and Conductive Human-Based Protein Hybrid Hydrogels.

Annabi Nasim N Shin Su Ryon SR Tamayol Ali A Miscuglio Mario M Bakooshli Mohsen Afshar MA Assmann Alexander A Mostafalu Pooria P Sun Jeong-Yun JY Mithieux Suzanne S Cheung Louis L Tang Xiaowu Shirley XS Weiss Anthony S AS Khademhosseini Ali A Khademhosseini Ali A

Advanced materials (Deerfield Beach, Fla.) 20151109 1

A highly elastic hybrid hydrogel of methacryloyl-substituted recombinant human tropoelastin (MeTro) and graphene oxide (GO) nanoparticles are developed. The synergistic effect of these two materials significantly enhances both ultimate strain (250%), reversible rotation (9700°), and the fracture energy (38.8 ± 0.8 J m(-2) ) in the hybrid network. Furthermore, improved electrical signal propagation and subsequent contraction of the muscles connected by hybrid hydrogels are observed in ex vivo tes ...[more]

PMID: 26551969

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