Ontology highlight
ABSTRACT:
SUBMITTER: Schennach M
PROVIDER: S-EPMC4863917 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Schennach Moritz M Schneeberger Eva-Maria EM Breuker Kathrin K
Journal of the American Society for Mass Spectrometry 20160302 6
Electron capture dissociation was used to probe the structure, unfolding, and folding of KIX ions in the gas phase. At energies for vibrational activation that were sufficiently high to cause loss of small molecules such as NH3 and H2O by breaking of covalent bonds in about 5% of the KIX (M + nH)(n+) ions with n = 7-9, only partial unfolding was observed, consistent with our previous hypothesis that salt bridges play an important role in stabilizing the native solution fold after transfer into t ...[more]