Ontology highlight
ABSTRACT:
SUBMITTER: Pei J
PROVIDER: S-EPMC4864567 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Pei Jihua J Yan Jianfang J Jiang Yi Y
Archaea (Vancouver, B.C.) 20160428
The Lon protease is highly evolutionarily conserved. However, little is known about Lon in the context of gut microbial communities. A gene encoding a Lon-like protease (Lon-like-Ms) was identified and characterized from Methanobrevibacter smithii, the predominant archaeon in the human gut ecosystem. Phylogenetic and sequence analyses showed that Lon-like-Ms and its homologs are newly identified members of the Lon family. A recombinant form of the enzyme was purified by affinity chromatography, ...[more]