IL17A and IL17F gene polymorphisms in patients with rheumatoid arthritis.
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ABSTRACT:
SUBMITTER: Pawlik A
PROVIDER: S-EPMC4864924 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
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IL17A and IL17F gene polymorphisms in patients with rheumatoid arthritis.
Pawlik Andrzej A Kotrych Daniel D Malinowski Damian D Dziedziejko Violetta V Czerewaty Michal M Safranow Krzysztof K
BMC musculoskeletal disorders 20160511
<h4>Background</h4>Interleukin-17 plays important role in the pathogenesis of rheumatoid arthritis (RA). The aim of this study was to examine the associations between polymorphisms in the IL17A and IL17F genes and RA.<h4>Methods</h4>We examined 422 RA patients and 337 subjects as a control group. Single nucleotide polymorphism (SNP) in the IL17A (rs2275913) and IL17F (rs763780, rs11465553, rs2397084) genes were genotyped using TaqMan genotyping assays from Life Technologies Genomic.<h4>Results</ ...[more]
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