Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk.
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ABSTRACT:
SUBMITTER: Stern JH
PROVIDER: S-EPMC4864949 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Publications
Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk.
Stern Jennifer H JH Rutkowski Joseph M JM Scherer Philipp E PE
Cell metabolism 20160501 5
Metabolism research has made tremendous progress over the last several decades in establishing the adipocyte as a central rheostat in the regulation of systemic nutrient and energy homeostasis. Operating at multiple levels of control, the adipocyte communicates with organ systems to adjust gene expression, glucoregulatory hormone exocytosis, enzymatic reactions, and nutrient flux to equilibrate the metabolic demands of a positive or negative energy balance. The identification of these mechanisms ...[more]
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