Data on sulforaphane treatment mediated suppression of autoreactive, inflammatory M1 macrophages.
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ABSTRACT:
SUBMITTER: Pal S
PROVIDER: S-EPMC4865660 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
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Data on sulforaphane treatment mediated suppression of autoreactive, inflammatory M1 macrophages.
Pal Sanjima S Konkimalla V Badireenath VB
Data in brief 20160425
Any chronic, inflammatory, autoimmune disease (e.g. arthritis) associated pathogenesis directs uncontrolled accumulation of both soluble forms of collagens in the synovial fluids and M1 macrophages around inflamed tissues. Despite of few studies demonstrating efficiency of Sulforaphane (SFN) in suppressing arthritis associated collagen restricted T cells or fibroblasts, its effects on macrophage polarity and plasticity are less understood. Recently, we reported regulation of phenotypic and funct ...[more]
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