Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity.
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ABSTRACT:
SUBMITTER: Xu D
PROVIDER: S-EPMC4866517 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
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Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity.
Xu Dawei D Jiang Linhai L Singh Anju A Dustin Derek D Yang Miao M Liu Ling L Lund Reidar R Sellati Timothy J TJ Dong He H
Chemical communications (Cambridge, England) 20150101 7
This work demonstrates a design strategy to optimize antimicrobial peptides with an ideal balance of minimal cytotoxicity, enhanced stability, potent cell penetration and effective antimicrobial activity, which hold great promise for the treatment of intracellular microbial infections and potentially systemic anti-infective therapy. ...[more]
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