Ontology highlight
ABSTRACT:
SUBMITTER: Tsvetkov V
PROVIDER: S-EPMC4867883 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Tsvetkov Vladimir V Pozmogova Galina G Varizhuk Anna A
Journal of biomolecular structure & dynamics 20150714 4
Conformational changes in DNA G-quadruplex (GQ)-forming regions affect genome function and, thus, compose an interesting research topic. Computer modelling may yield insight into quadruplex folding and rearrangement, particularly molecular dynamics simulations. Here, we show that specific parameters, which are distinct from those commonly used in DNA conformational analyses, must be introduced for adequate interpretation and, most importantly, convenient visual representation of the quadruplex m ...[more]