Dataset Information

Adherence to ARRIVE Guidelines in Chinese Journal Reports on Neoplasms in Animals.

ABSTRACT:

Background

The Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines were published in 2010 with the aim of improving the quality of studies involving animals. However, how well Chinese studies involving animal neoplasms adhere to these guidelines has not been assessed.

Objective

To evaluate the reporting quality of such experiments published between 2010 and 2012 in Chinese journals with support from the National Natural Science Foundation of China.

Methods

We searched the Chinese Science Citation and Chinese Journal Full-Text Databases for articles published between 2010 and 2012 involving neoplasms in animals. The data were extracted into pre-prepared forms. Reporting quality was assessed using the ARRIVE checklist-39 items plus information on blinding.

Results

Three hundred and ninety-six animal studies were included in the analysis: 127 studies published in 2010, 140 studies published in 2011, and 129 studies published in 2012. The range of ARRIVE score is from 12 to 27 with a maximum possible score of 40. Studies published in 2012 (P = 0.012), 2011 (P = 0.015), 2010, July~Dec (P<0.017) had a significantly larger ARRIVE checklist score than those published in Jan.~June, 2010, respectively.

Conclusions

Experiments involving neoplasms in animals published in Chinese journals generally have not comprehensively reported the information recommended by the ARRIVE guidelines. We strongly recommend that researchers conducting such studies report this information.

SUBMITTER: Liu Y

PROVIDER: S-EPMC4868299 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Publications

Adherence to ARRIVE Guidelines in Chinese Journal Reports on Neoplasms in Animals.

Liu Yali Y Zhao Xingxing X Mai Yuefen Y Li Xinxin X Wang Jin J Chen Lili L Mu Jing J Jin Gengxue G Gou Hongping H Sun Wanting W Feng Yuchen Y

PloS one 20160516 5

<h4>Background</h4>The Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines were published in 2010 with the aim of improving the quality of studies involving animals. However, how well Chinese studies involving animal neoplasms adhere to these guidelines has not been assessed.<h4>Objective</h4>To evaluate the reporting quality of such experiments published between 2010 and 2012 in Chinese journals with support from the National Natural Science Foundation of China.<h4>Methods</h ...[more]

PMID: 27182788

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Project description:Preclinical research within the area of urethral tissue engineering has not yet been successfully translated into an efficient therapeutic option for patients. This gap could be attributed, in part, to inadequate design and reporting of the studies employing laboratory animals. In this study, a systematic review was conducted to investigate the quality of reporting in preclinical studies utilizing tissue engineering approaches for urethral repair. The scope was on studies performed in rabbits, published between January 2014 and March 2020. Quality assessment of the data was conducted according to the Animal Research: Reporting of in Vivo Experiments (ARRIVE) guidelines by the scoring of a 38-item checklist in different categories. A total of 28 articles that fulfilled the eligibility criteria were included in the study. The range of ARRIVE score was from 0 to 100, taking into consideration having reported the item in question or not. The mean checklist score was 53%. The items that attained the highest scores included the number of animals utilized, the size of control and experimental groups, and the definition of experimental outcomes. The least frequently reported items included the data regarding the experimental procedure, housing and husbandry, determination and justification of the number of animals, and reporting of adverse events. Surprisingly, full disclosure about ethical guidelines and animal protocol approval was missing in 54% of the studies. No paper stated the sample size estimation. Overall, our study found that a large number of studies display inadequate reporting of fundamental information and that the quality of reporting improved marginally over the study period. We encourage a comprehensive implementation of the ARRIVE guidelines in animal studies exploring tissue engineering for urethral repair, not only to facilitate effective translation of preclinical research findings into clinical therapies, but also to ensure compliance with ethical principles and to minimize unnecessary animal studies.

Dataset Information

Adherence to ARRIVE Guidelines in Chinese Journal Reports on Neoplasms in Animals.

Background

Objective

Methods

Results

Conclusions

Publications

Adherence to ARRIVE Guidelines in Chinese Journal Reports on Neoplasms in Animals.

Similar Datasets

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