Ontology highlight
ABSTRACT:
SUBMITTER: Guglin M
PROVIDER: S-EPMC4869919 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Guglin Maya M Rajagopalan Navin N Anaya Paul P Charnigo Richard R
Pulmonary circulation 20160601 2
In this article, we present the rationale and design of the Sildenafil HF trial (ClinicalTrials.gov identifier: NCT02304705). We will randomize patients with heart failure and reactive pulmonary hypertension (pulmonary capillary wedge pressure > 15 mmHg, pulmonary vascular resistance > 3 Wood units) into two groups: the treatment group receiving sildenafil 20 mg 3 times a day and a matching placebo group. The duration of intervention will be 3 months. The primary outcome is 6-minute walk distanc ...[more]