Ontology highlight
ABSTRACT:
SUBMITTER: Gunes S
PROVIDER: S-EPMC4870443 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Journal of assisted reproduction and genetics 20160303 5
Infertility is a complex disorder with multiple genetic and environmental causes. Although some specific mutations have been identified, other factors responsible for sperm defects remain largely unknown. Despite considerable efforts to identify the pathophysiology of the disease, we cannot explain the underlying mechanisms of approximately half of infertility cases. This study reviews current data on epigenetic regulation and idiopathic male infertility. Recent data have shown an association be ...[more]