Ontology highlight
ABSTRACT:
SUBMITTER: Okumura N
PROVIDER: S-EPMC4870691 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Okumura Naoki N Sakamoto Yuji Y Fujii Keita K Kitano Junji J Nakano Shinichiro S Tsujimoto Yuki Y Nakamura Shin-Ichiro S Ueno Morio M Hagiya Michio M Hamuro Junji J Matsuyama Akifumi A Suzuki Shingo S Shiina Takashi T Kinoshita Shigeru S Koizumi Noriko N
Scientific reports 20160518
The corneal endothelium maintains corneal transparency; consequently, its dysfunction causes severe vision loss. Tissue engineering-based therapy, as an alternative to conventional donor corneal transplantation, is anticipated to provide a less invasive and more effective therapeutic modality. We conducted a preclinical study for cell-based therapy in a primate model and demonstrated regeneration of the corneal endothelium following injection of cultured monkey corneal endothelial cells (MCECs) ...[more]