Ontology highlight
ABSTRACT:
SUBMITTER: Qie Y
PROVIDER: S-EPMC4872535 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Qie Yaqing Y Yuan Hengfeng H von Roemeling Christina A CA Chen Yuanxin Y Liu Xiujie X Shih Kevin D KD Knight Joshua A JA Tun Han W HW Wharen Robert E RE Jiang Wen W Kim Betty Y S BY
Scientific reports 20160519
Nanomedicine is a burgeoning industry but an understanding of the interaction of nanomaterials with the immune system is critical for clinical translation. Macrophages play a fundamental role in the immune system by engulfing foreign particulates such as nanoparticles. When activated, macrophages form distinct phenotypic populations with unique immune functions, however the mechanism by which these polarized macrophages react to nanoparticles is unclear. Furthermore, strategies to selectively ev ...[more]