Ontology highlight
ABSTRACT:
SUBMITTER: Waters AM
PROVIDER: S-EPMC4873350 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Waters Alicia M AM Stewart Jerry E JE Atigadda Venkatram R VR Mroczek-Musulman Elizabeth E Muccio Donald D DD Grubbs Clinton J CJ Beierle Elizabeth A EA
Molecular cancer therapeutics 20160212 5
Rare tumors of solid organs remain some of the most difficult pediatric cancers to cure. These difficult tumors include rare pediatric renal malignancies, such as malignant rhabdoid kidney tumors (MRKT) and non-osseous renal Ewing sarcoma, and hepatoblastoma, a pediatric liver tumor that arises from immature liver cells. There are data in adult renal and hepatic malignancies demonstrating the efficacy of retinoid therapy. The investigation of retinoic acid therapy in cancer is not a new strategy ...[more]