Ontology highlight
ABSTRACT:
SUBMITTER: Stiller SB
PROVIDER: S-EPMC4873616 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Cell metabolism 20160501 5
The mitochondrial inner membrane harbors three protein translocases. Presequence translocase and carrier translocase are essential for importing nuclear-encoded proteins. The oxidase assembly (OXA) translocase is required for exporting mitochondrial-encoded proteins; however, different views exist about its relevance for nuclear-encoded proteins. We report that OXA plays a dual role in the biogenesis of nuclear-encoded mitochondrial proteins. First, a systematic analysis of OXA-deficient mitocho ...[more]