Ontology highlight
ABSTRACT:
SUBMITTER: Ashkani J
PROVIDER: S-EPMC4873817 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Ashkani Jahanshah J Naidoo Kevin J KJ
Scientific reports 20160520
Aberrant glycosylation in tumours stem from altered glycosyltransferase (GT) gene expression but can the expression profiles of these signature genes be used to classify cancer types and lead to cancer subtype discovery? The differential structural changes to cellular glycan structures are predominantly regulated by the expression patterns of GT genes and are a hallmark of neoplastic cell metamorphoses. We found that the expression of 210 GT genes taken from 1893 cancer patient samples in The Ca ...[more]