Ontology highlight
ABSTRACT:
SUBMITTER: Adhikari K
PROVIDER: S-EPMC4874031 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Nature communications 20160519
We report a genome-wide association scan for facial features in ∼6,000 Latin Americans. We evaluated 14 traits on an ordinal scale and found significant association (P values<5 × 10(-8)) at single-nucleotide polymorphisms (SNPs) in four genomic regions for three nose-related traits: columella inclination (4q31), nose bridge breadth (6p21) and nose wing breadth (7p13 and 20p11). In a subsample of ∼3,000 individuals we obtained quantitative traits related to 9 of the ordinal phenotypes and, also, ...[more]