Emerging Concepts in Paracrine Mechanisms in Regenerative Cardiovascular Medicine and Biology.
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ABSTRACT:
SUBMITTER: Hodgkinson CP
PROVIDER: S-EPMC4874329 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Publications
Emerging Concepts in Paracrine Mechanisms in Regenerative Cardiovascular Medicine and Biology.
Hodgkinson Conrad P CP Bareja Akshay A Gomez José A JA Dzau Victor J VJ
Circulation research 20160101 1
In the past decade, substantial evidence supports the paradigm that stem cells exert their reparative and regenerative effects, in large part, through the release of biologically active molecules acting in a paracrine fashion on resident cells. The data suggest the existence of a tissue microenvironment where stem cell factors influence cell survival, inflammation, angiogenesis, repair, and regeneration in a temporal and spatial manner. ...[more]
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