Ontology highlight
ABSTRACT:
SUBMITTER: Dorn GW
PROVIDER: S-EPMC4876055 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Journal of molecular and cellular cardiology 20151122
Mitochondria can undergo autophagic elimination for differing reasons, e.g. as part of a cell-wide macroautophagic response, as part of mitochondrial turnover during metabolic remodeling, or in the case of selective mitophagic destruction of dysfunctional mitochondria, during mitochondrial quality control. Multiple mechanistically distinct pathways converge upon, and activate, mitochondrial autophagy. Here, the evidence supporting a role for the prototypical mitochondrial quality control pathway ...[more]