Ontology highlight
ABSTRACT:
SUBMITTER: Economopoulou P
PROVIDER: S-EPMC4876265 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Annals of translational medicine 20160501 9
Head and neck squamous cell carcinoma (HNSCC) carries a poor prognosis, with low survival rates for advanced stage tumors and minimal improvement in survival trends through the past decades. It is becoming increasingly clear that HNSCC oncogenesis and evolution is characterized by profound immune defects, as cancer cells evade immunosurveillance due to accumulation of genetic mutations and tumor heterogeneity. Improved understanding of the role of the immune system in cancer has led to the ident ...[more]