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Human papillomavirus DNA positivity and seropositivity in rural Chinese men and women: a population-based cross-sectional study.


ABSTRACT: Data on simultaneous analysis of human papillomavirus (HPV) DNA and serology and the correlations within a single general population are limited. Among 1603 men and 2187 women enrolled from rural China, serum antibodies against bacterially derived GST-L1 fusion proteins of HPV were assessed with multiplexed serology and HPV DNA was evaluated with PCR-based sequencing. Few subjects were dually positive to HPV DNA and serum antibodies for any HPV (6.6% of men and 3.1% of women). The proportion of men ever having been infected with any HPV (DNA and/or antibody positive) was higher than that of women (71.0% vs. 65.2%, P?

SUBMITTER: Liu F 

PROVIDER: S-EPMC4876329 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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Human papillomavirus DNA positivity and seropositivity in rural Chinese men and women: a population-based cross-sectional study.

Liu Fangfang F   Deng Qiuju Q   Zhang Chanyuan C   Pan Yaqi Y   Liu Ying Y   He Zhonghu Z   Sun Min M   Liu Mengfei M   Li Jingjing J   Li Xiang X   Zhang Chaoting C   Hang Dong D   Ning Tao T   Guo Chuanhai C   Liang Yongmei Y   Xu Ruiping R   Zhang Lixin L   Cai Hong H   Ke Yang Y  

Scientific reports 20160523


Data on simultaneous analysis of human papillomavirus (HPV) DNA and serology and the correlations within a single general population are limited. Among 1603 men and 2187 women enrolled from rural China, serum antibodies against bacterially derived GST-L1 fusion proteins of HPV were assessed with multiplexed serology and HPV DNA was evaluated with PCR-based sequencing. Few subjects were dually positive to HPV DNA and serum antibodies for any HPV (6.6% of men and 3.1% of women). The proportion of  ...[more]

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