Ontology highlight
ABSTRACT:
SUBMITTER: Xie Y
PROVIDER: S-EPMC4876965 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Xie Yuliang Y Nama Nitesh N Li Peng P Mao Zhangming Z Huang Po-Hsun PH Zhao Chenglong C Costanzo Francesco F Huang Tony Jun TJ
Small (Weinheim an der Bergstrasse, Germany) 20151230 7
An acoustically actuated, bubble-based technique is developed to investigate the deformability of cells suspended in microfluidic devices. A microsized bubble is generated by an optothermal effect near the targeted cells, which are suspended in a microfluidic chamber. Subsequently, acoustic actuation is employed to create localized acoustic streaming. In turn, the streaming flow results in hydrodynamic forces that deform the cells in situ. The deformability of the cells is indicative of their me ...[more]