The type of the functional cardiovascular response to upright posture is associated with arterial stiffness: a cross-sectional study in 470 volunteers.

ABSTRACT:

Background

In a cross-sectional study we examined whether the haemodynamic response to upright posture could be divided into different functional phenotypes, and whether the observed phenotypes were associated with known determinants of cardiovascular risk.

Methods

Volunteers (n = 470) without medication with cardiovascular effects were examined using radial pulse wave analysis, whole-body impedance cardiography, and heart rate variability analysis. Based on the passive head-up tilt induced changes in systemic vascular resistance and cardiac output, the principal determinants of blood pressure, a cluster analysis was performed.

Results

The haemodynamic response could be clustered into 3 categories: upright increase in vascular resistance and decrease in cardiac output

SUBMITTER: Tahvanainen AM 

PROVIDER: S-EPMC4877753 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature