Ontology highlight
ABSTRACT:
SUBMITTER: Bik-Multanowski M
PROVIDER: S-EPMC4878308 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Bik-Multanowski Miroslaw M Pietrzyk Jacek J JJ Midro Alina A
Journal of Alzheimer's disease : JAD 20150101 1
Morphological abnormalities observed typically in the brains of adults with Down syndrome are identical with those present in patients with Alzheimer's disease. However, only some adults with Down syndrome suffer from early dementia, whereas others remain unaffected. We aimed to identify the genomic background responsible for this observation. We performed cognitive assessment and genome expression analysis of blood mononuclear cells in seniors with Down syndrome. Unaffected elderly patients and ...[more]