Ontology highlight
ABSTRACT:
SUBMITTER: Rafii S
PROVIDER: S-EPMC4878406 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Rafii Shahin S Butler Jason M JM Ding Bi-Sen BS
Nature 20160101 7586
Endothelial cells that line capillaries are not just passive conduits for delivering blood. Tissue-specific endothelium establishes specialized vascular niches that deploy sets of growth factors, known as angiocrine factors. These cues participate actively in the induction, specification, patterning and guidance of organ regeneration, as well as in the maintainance of homeostasis and metabolism. When upregulated following injury, they orchestrate self-renewal and differentiation of tissue-specif ...[more]