Molecular Epidemiology and Genetic Characteristics of Various blaPER Genes in Shanghai, China.
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ABSTRACT:
SUBMITTER: Xie L
PROVIDER: S-EPMC4879356 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Publications
Molecular Epidemiology and Genetic Characteristics of Various blaPER Genes in Shanghai, China.
Xie Lianyan L Wu Jun J Zhang Fangfang F Han Lizhong L Guo Xiaokui X Ni Yuxing Y Sun Jingyong J
Antimicrobial agents and chemotherapy 20160523 6
We describe the genetic characteristics and possible transmission mechanism of blaPER in 25 clinical Gram-negative bacilli in Shanghai. blaPER, including blaPER-1, blaPER-3, and blaPER-4, was located chromosomally or in different plasmids. Tn1213 harboring blaPER-1 was first identified in two Proteus mirabilis isolates in China. The other blaPER variants were preceded by an ISCR1 element inside the complex class 1 integron associated with IS26, Tn21, Tn1696, and a miniature inverted-repeat trans ...[more]
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