Molecular Architecture of the Retroviral Capsid.
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ABSTRACT:
SUBMITTER: Perilla JR
PROVIDER: S-EPMC4879823 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Publications
Molecular Architecture of the Retroviral Capsid.
Perilla Juan R JR Gronenborn Angela M AM
Trends in biochemical sciences 20160330 5
Retroviral capsid cores are proteinaceous containers that self-assemble to encase the viral genome and a handful of proteins that promote infection. Their function is to protect and aid in the delivery of viral genes to the nucleus of the host, and, in many cases, infection pathways are influenced by capsid-cellular interactions. From a mathematical perspective, capsid cores are polyhedral cages and, as such, follow well-defined geometric rules. However, marked morphological differences in shape ...[more]
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