Ontology highlight
ABSTRACT:
SUBMITTER: Aragones G
PROVIDER: S-EPMC4881456 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Aragonès Gemma G Auguet Teresa T Armengol Sandra S Berlanga Alba A Guiu-Jurado Esther E Aguilar Carmen C Martínez Salomé S Sabench Fátima F Porras José Antonio JA Ruiz Maikel Daniel MD Hernández Mercé M Sirvent Joan Josep JJ Del Castillo Daniel D Del Castillo Daniel D Richart Cristóbal C
International journal of molecular sciences 20160427 5
Recent reports suggest a role for the Patatin-like phospholipase domain-containing protein 3 (PNPLA3) in the pathology of non-alcoholic fatty liver disease (NAFLD). Lipid deposition in the liver seems to be a critical process in the pathogenesis of NAFLD. The aim of the present work was to evaluate the association between the liver PNPLA3 expression, key genes of lipid metabolism, and the presence of NAFLD in morbidly obese women. We used real-time polymerase chain reaction (PCR) analysis to ana ...[more]